But the data is clear, and avoiding it does more harm than addressing it directly
Common Side Effects of GLP-1 Weight Loss Medications Share Starting a GLP-1 medication can feel both exciting and uncertain
Orforglipron was originally discovered by Chugai Pharmaceutical and licensed by Lilly in 2018
For medications that must be taken before the first meal of the day, patients who practice intermittent fasting may need to adjust their medication schedule accordingly
(Source: In August 2025 , Viking Therapeutic announced encouraging mid-stage trial results for its experimental oral/injectable weight loss drug VK2735, which achieved up to 12.2% body weight reduction over 12 weeks, through shares dropped due to higher treatment discontinuation from gastrointestinal side effects
Clients using Semaglutide GLP-1 for weight management have achieved substantial, sustained reductions in body weight over time