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It is a living organ with a complex structural framework made primarily of collagen and elastin fibers embedded in a gel-like substance called the extracellular matrix

This compound is typically supplied as a lyophilized peptide and should be stored at 4 F (20 C) or below, protected from heat, moisture, and light

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The liberation of Nrf2 from Keap1 allows Nrf2 accumulation and translocation to the nucleus (Cuadrado et al., 2019