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Meaningful weight loss typically begins at the 4mg dose (week 5-8), accelerates at 8mg (week 12-16), and reaches peak effect at 12mg after 24+ weeks

According to the topline results of Phase-3 TRIUMPH-2 study, after 80 weeks of treatment, the once-weekly drug highest strength 12 mg helped patients to shed 20.8 per ent (22.5 kg) of their body weight, followed by 19.1 per cent (20.6 kg) and 12.7 per cent (13.5 kg) with the 9 mg and 4 mg dose respectively

Gasiorek A et al

Mounjaro mimics this hormone alongside GLP-1