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Hatcher calls it the "worst medication I've ever taken," but it's "infinitely cheaper" than GLP-1s and similarly addresses insulin resistance, Pea says

VANQUISH-1 is fully enrolled with approximately 4,500 patients, and the Phase 3 oral program is expected to begin in Q3 2026, with maintenance dosing results also due that quarter

It can also cause the urine, breath, and sweat to have a fishy odor

Retatrutide remains under clinical investigation, primarily through trials conducted by its developer, Eli Lilly

The choice between them should be based on the GLP-1 agonist comparison, not the levocarnitine addition