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What aspects of the trial design were most important for ensuring a fair, blinded comparison between the two agents, particularly regarding dose escalation and patient selection

Around week 8 to 12, some patients notice weight loss slowing or plateauing temporarily

Systematic screening and documentation Every patient with liver disease should undergo standardized assessment of smoking status at initial and follow-up visits

Dosage: Higher cell doses are thought to increase effect

-4F (-20C) acceptable Duration Up to 6 months at -80C or ~1 month at -20C

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