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10.1016/j.copbio.2012.08.005 [DOI] [PubMed] [Google Scholar] McGuire S

This is why some of the medications can be dosed just once weekly, and why patients benefit from the consistent blood-sugar-lowering and appetite-suppressing effects

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For example, Regeneron recently showed combining its antibody trevogrumab with semaglutide helped preserve lean mass while increasing fat mass loss

The point is not to catastrophise its to avoid white-knuckling through a solvable problem