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Am J Physiol Endocrinol Metab (2009) 296:E4739.10.1152/ajpendo.90636.2008 184 OvertonHABabbsAJDoelSMFyfeMCGardnerLSGriffinGet alDeorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents

(2015) Icariin exerts an antidepressant effect in an unpredictable chronic mild stress model of depression in rats and is associated with the regulation of hippocampal neuroinflammation

The drug was based on an active ingredient that had been available for many years at a much lower cost

Puede emplearse como nico tratamiento (monoterapia) o en combinacin con otros frmacos para la diabetes , incluyendo insulina

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