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Interestingly, TAM were shown to secrete several pro-angiogenic cytokines and growth factors, such as VEGF (4446), MMP (4648), IL-10 (40, 46, 47, 49, 50), IL-8 (45, 46), FGF2 (45, 51, 52) and placental growth factor (PlGF) (52), allowing them to modulate angiogenic pathways

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Table 1 ), suggesting the recombinant AsGGT1 and AsGGT3 exhibit a weak activity to deglutamylate -glutamyl- S -allyl-L-cysteine sulfoxide

Tokura, Y., Nakayama, Y., Fukada, S., Nara, N., Yamamoto, H., Matsuda, R., & Hara, T

Implausibility of radical life extension in humans in the twenty-first century

Cell 173 , 7489.e20 (2018)