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PMID: 9849822 | doi:10.1530/eje.0.1390552 Johansen PB et al

The vitamin is involved in the production of neurotransmitters, which can help balance mood, improve focus, and even alleviate symptoms of depression

These data help to explain why an excess of methionine does not lead to a higher elevation of homocysteine in patients with an alteration of the remethylation pathway (caused by folate or cobalamin deficiency and/or by a partial congenital MTHFR defect)