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Enhanced inhibition of syngeneic murine tumors by combinatorial therapy with genetically engineered HSV-1 expressing CCL2 and IL-12

Common Side Effects (affecting less than 5% of patients): Mild injection site irritation or bruising Temporary headache (usually related to detox reactions) Mild nausea or stomach discomfort Brief dizziness or lightheadedness Rare but Serious Reactions : Allergic reactions (rash, difficulty breathing, swelling) Significant blood pressure changes Severe abdominal cramping Drug Interactions : Glutathione can potentially interact with certain chemotherapy drugs and may affect blood clotting in patients taking anticoagulants

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A non-GLP-1 alternative with different side effect profiles

No patient had adverse effects of l-carnitine during the study period