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Orforglipron vs Farxiga: A New Chapter in Oral Diabetes Therapy Big news from the diabetes frontEli Lillys oral GLP-1 candidate Orforglipron just outperformed Farxiga (dapagliflozin) in two Phase III trials

Keywords: glucagon-like peptide-1 receptor agonists, ocular diseases, glaucoma, diabetic retinopathy, mechanism 1 Introduction Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from gut enteroendocrine cells and regulates blood sugar by increasing insulin while reducing glucagon secretion and inhibiting stomach emptying and food intake (Drucker, 2022)

thus the 130 mg/dL ethanol concentration in this patient should decline to 80 mg/dL (a difference of 50 mg/dL) in ~2.5 hours Case 16.3 1

2017;60(Suppl 1):S69

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