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Check that the medication is clear and colorless, and check that the expiration date hasnt passed

SBP reduction was mostly mediated by weight loss (7794%) in SURPASS-1, -2 and -3, while mechanisms independent from weight loss accounted for most of the tirzepatide benefit on SBP in SURPASS-4 and -5 (57 and 73%, respectively) [77]

Patients should not stop or change these medications without consulting their healthcare provider

However, retatrutide is still investigational and is not currently approved in the UK

reports on their association are conflicting