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___ AP video journalist Javier Arciga contributed to this story from San Diego ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institutes Science and Educational Media Group and the Robert Wood Johnson Foundation

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To overcome these difficulties, there is ongoing research into the use of in vivo imaging techniques, such as dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) and arterial spin labeling MRI (ASL MRI), which may easily detect subtle changes in BBB permeability