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Conversely, inhibition of mitophagy can lead to mitochondrial dysfunction, trigger apoptosis, and ultimately increase treatment sensitivity [46]

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Skin inflammation in acne occurs when clogged pores trigger an immune response to bacteria, excess oil, or irritation

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7 Clinical note: These mechanisms are derived from preclinical models

Dietary polyphenols and their role in oxidative stress-induced human diseases: insights into protective effects, antioxidant potentials and mechanism(s) of action