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Hair thinning has been reported among people using GLP-1 medications, particularly those experiencing rapid or significant weight loss

Finally, PI3K/Akt/GSK3 signaling pathway was restored by tirzepatide

Briefly, our findings did not detect a high signal for AEs of mood disorders associated with GLP-1 RAs

The key difference is intention: titration aims to find your dose, while maintenance aims to sustain your results

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Early reports suggest its well-tolerated, but long-term safety is still being evaluated