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Keywords: GLP-1RA, Model-based meta-analysis, Obesity, Weight reduction Graphical abstract Highlights Offers a detailed comparison of the efficacy, potential influencing factors and safety profiles among various GLP-1RAs

If you develop symptoms of severe hyperglycaemia (excessive thirst, frequent urination, fatigue) or feel very unwell, contact your GP urgently or call NHS 111 for same-day assessment

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Patients who discover that they are pregnant while still taking a prescription GLP-1 medication should contact their care providers right away

(N=166) found that GH replacement therapy raised fasting glucose by a mean of 0.3 mmol/L over 12 months in GH-deficient adults [7]