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There is also recent data which suggest that genetic alterations of the receptor by which B12 is transported into nerve tissue and the brain, may lead to a lower B12 uptake

This higher dose can be administered as a single 100mg injection in the morning or split into two 50mg doses taken 12 hours apart (morning and afternoon)

These trials included both single-dose pharmacokinetic studies and long-term efficacy trials extending up to 24 weeks of continuous administration

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The compact and lightweight format also supports efficient handling, storage, and repeated evaluation during extended research projects