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33.1% achieved 10% or more FDA-approved as Saxenda (2014) for chronic weight management Also approved for adolescent obesity (ages 12+) The weight loss advantage of liraglutide over exenatide is approximately 2-3 fold when comparing the obesity-specific liraglutide dose to exenatide's diabetes-dose weight effects

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The article explains that GLP-1 receptor agonists alter normal gut motility and fluid balance, and that in some patients the result is accelerated colonic transit further down the tract