[1] [2] In the UK, according to their Summary of Product Characteristics (SmPCs), these medications are licensed for adults with a body mass index (BMI) of 30 kg/m or above, or 27 kg/m or above in the presence of weight-related comorbidities such as type 2 diabetes, hypertension, or obstructive sleep apnoea
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More severe deficiency manifests as a peripheral neuropathy, seizures, and a sideroblastic anemia
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