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The potential explanation for sex differences in the IGF-1 signaling pathway on aging as well as response to other age-delaying interventions is unclear, but unique interactions of candidate pathways and targets with sex hormones could explain in part these disparate effects

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In most cases it is considered safe to take supplements through injections to make up for this deficiency, but if you want to know more about it then this article is for you

However, this duration can differ among individuals