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Never inject into the exact same spot within 12 weeks

[6] [7] There are no known disease states or conditions in which biotin supplementation is explicitly contraindicated, since biotin is a natural vitamin required for normal metabolism

doi: 10.2174/1381612826666200526150113 110 Pourteymour Fard TabriziFHajizadeh-SharafabadFVaeziMJafari-VayghanHAlizadehMMalekiV

[1] Tissue distribution of carnitine-biosynthetic enzymes in humans [edit] The tissue distribution of carnitine-biosynthetic enzymes in humans indicates TMLD to be active in the liver, heart, muscle, brain and highest in the kidneys

Spatial segregation and kinetic control determine whether these species act as signals (e.g., H 2 O 2 microgradients) or cause damage (e.g., OH near DNA)