If an independent assessment is not available, based on the findings from Chappel et al
Vitamin D supports calcium absorption and plays a role in bone and muscle function
Children: At the beginning of treatment, the total dose is 1 mg to 5 mg injected into the muscle over a period of 2 or more weeks, in doses of 100 mcg at a time
The investigators attributed the angiogenic effect to upregulation of vascular endothelial growth factor receptor 2 (VEGFR2) and activation of the Aktendothelial nitric oxide synthase (eNOS) signaling pathway
Suganuma K, Nakajima H, Ohtsuki M, Imokawa G (2010) Astaxanthin attenuates the UVA-induced up-regulation of matrix-metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts
Further development and experimentation surprisingly led to the present invention wherein with the help of selection of suitable ingredients in appropriate amounts, suitable In-vitro release pattern was obtained wherein even with lower doses, one can deliver sufficient GHK-Cu so that at least 100 micrograms, prefearably 200 micrograms and most preferably 300 micrograms of GHK-Cu remain at the end of 24 hrs