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That is a fact, Martin-Ogburn told the committee, adding that there were also external factors

Endogenous morphine tempers excitability and, through nitric oxide coupling, appears capable of directly modulating mitochondrial respiration and preserving metabolic homeostasis

By leading the conversation with weight and self-image rather than health, H&H is encouraging the discourse that being overweight is a choice, a moral failing even, and one that anyone in their right mind should be willing to take drugs to combat no matter what the potential side effects