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doi: 10.1080/19490976.2022.2085961

It has been suggested that the accumulation of D-2-hydroxyglutaric acid may contribute to impaired mitochondrial energy metabolism, increased oxidative stress, activation of N-methyl-D-aspartate (NMDA) receptors, and increased glutamate uptake, which may have toxic effects on cells and nerves [54], leading to the occurrence of epilepsy

Early studies from the late 1990s reported that supplementation at 12 grams per day improved mood and reduced fatigue in patients with major depressive disorder, as evidenced by reductions in Hamilton Depression Rating Scale scores by about 2030% over 48 weeks [5]

Glutathionmangel: Ursachen, Symptome und Folgen Unter einem Glutathionmangel leiden vor allem Senioren und Menschen, die erhhtem oxidativen Stress ausgesetzt sind

Differential regulation of glutamic acid decarboxylase mRNA and tyrosine hydroxylase mRNA expression in the aged manganese-treated rats