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The mean follow-up on-treatment was 181 days (median 155 days, IQR 71 to 290 days) for tirzepatide initiators and 174 days (median 148 days, IQR 82 to 254 days) for semaglutide initiators

Similarly, patients with GH deficiency are at a substantially increased risk of developing insulin resistance and obesity, principally due to a lack of GH-mediated lipolytic effect on adipose tissue (46)

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The post-menopausal state is marked by relative insulin resistance, increased systemic inflammation, and altered hunger signaling

What should I do if I miss a weekly dose during the dose schedule