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The culture medium was then replaced with fresh culture medium containing various concentrations (based on OA: 0.01, 0.1, 0.5, 1, 2, 5, 10, 20, 50 g/mL) of free OA, OA-NPs or OA-NPs@OA

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Apply daily SPF 50, limit sun/heat exposure for 48 hours, avoid harsh exfoliants for 72 hours, and hydrate well