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Moreover, NAD+ is also a key player in redox reactions, and its depletion is thought to contribute to the development of oxidative stress

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However, the two mitochondrial-localised sequences, found in Xenopus tropicalis (Vertebrata) and Sycon ciliatum (Calcarea), are each the most divergent within their respective clades (indicated on Fig

The WT or mutant constructs were transiently transfected using Lipofectamine 2000 transfection reagent as previous described 25

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