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The Deseq2 package in R was employed for the calculation of log2 fold changes in transcript expression

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Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression

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This was supported by high levels of VEGF in prostate cancer patients with lymph node metastases (187)