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doi: 10.1038/nrgastro.2017.88

Patients with NASH have increased TNF levels in both the circulation and in hepatic tissues, which correlate with disease severity and mortality 21

Die Realitt ist, dass alle verfgbaren Humandaten aus winzigen offenen Studien stammen und keine greren kontrollierten Trials existieren

Abstract 518: Erk5 S496 phosphorylation, but not Erk5 kinase or transcriptional activity, is responsible for promoting macrophage inflammation and mitochondrial dysfunction via upregulating novel site of Nrf2 K518 sumoylation

Iron or folate may also be needed

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