Li M, Chen X, Wang X, Wei X, Wang D, Liu X, et al
Gulcins research group effectively utilized this method with slight modifications
In different cell types, activation of necroptosis can be triggered by death receptors of the TNF family, including TNF receptor superfamily member 1A (TNFRSF1A/TNFR1), FAS, and TNF-related apoptosis-inducing ligand (TRAIL) receptors (TNF receptor superfamily member 10a [TNFRSF10A/TRAILR1] and TNF receptor superfamily member 10b [TNFRSF10B/TRAILR2]), that typically induce apoptosis
10.1021/acs.jafc.6b04888 84 LiL.FuW.-W.WuR.-T.SongY.-H.WuW.-Y.YinS.-H.et al (2019a)
Fewer chemicals mean fewer chances to react
The parent compound, acetaminophen, and its sulfate and glucuronide compounds (metabolites) are not harmful