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Ozempic: FDA-approved for the treatment of Type 2 Diabetes and to reduce the risk of major cardiovascular events (heart attack/stroke)

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It is missing three amino acids at the beginning of the chain, which makes it bind less to carrier proteins and more directly to IGF-1 receptors

Thus, in the well-fed state, insulin enhances the carbon flux through the pentose phosphate pathway, increasing NADPH production Note: insulin also promotes fatty acid synthesis, which depends on a continuous supply of NADPH

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