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Topical tranexamic acid, arbutin, kojic acid, and azelaic acid can all be helpful when addressing hyperpigmentation, either instead of hydroquinone or in tandem with it

The antitumor functions of natural killer (NK) cells are upregulated by the expression of c-Myc proteins, which are required for IL-2/IL-12-induced NK cell metabolism and function 138

This increased P-450 activity, as you might expect, results in an increased formation of NAPQI from the acetaminophen

Among these four isoforms, AK1C2 and AK1C3 share 87.9% amino acid sequence identity and both enzymes possess 3-hydroxysteroid dehydrogenase (3-HSD) activity and catalyze 5-dihydrotesterone reduction to produce 5-androstane-3,17-diol (3-diol) 30

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Ebadi M, Klangkalya B, Deupree JD