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Microbial modulation of tryptophan metabolism links gut microbiota to disease and its treatment

The pathogenesis of RIP involves multiple pathological processes, including radiation-induced excessive production of reactive oxygen species (ROS), leading to oxidative stress, which in turn triggers apoptosis and mucosal barrier disruption, as well as an inflammatory cascade centered on proinflammatory cytokines

The absolute number of DVT events across all 21 trials was small, which is exactly why the confidence interval stretches so wide, from 1.09 to 12.25

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