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Age appears to have minimal impact on elimination, with elderly patients showing similar pharmacokinetic profiles to younger adults
That doesnt mean that lower doses dont work
In as-treated analyses median follow-up was 1 year [0-2] for both new GLP-1 RA users and new SGLT-2 inhibitor users
doi: 10.1016/j.jacl.2021.05.007 268 WongCKMcLeanBABaggioLLKoehlerJAHammoudRRittigNet al
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Short-Term Effectiveness of Low Dose Liraglutide in Combination With Metformin Versus High Dose Liraglutide Alone in Treatment of Obese PCOS: Randomized Trial
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