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TRPM4 knockdown substantially reduced cellular inflammation, oxidative stress, and lipid peroxidation, thereby improving endothelial function and potentially modulating atherosclerosis progression

Es una molcula que se sintetiza naturalmente en el hgado, riones y cerebro a partir de aminocidos como la lisina y la metionina

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however, peripheral serotonin can indirectly modulate brain function and influence central neurotransmission through vagal pathways and neuro-endocrine signaling, although this relationship is complex and not fully understood (Sbrini et al., 2022)

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