They include: Carrying extra weight (your healthcare provider can let you know how much weight for your gender and height)
Monitor blood glucose levels more frequently, check ketones if advised by your healthcare team, and consider temporarily adjusting other diabetes medications (particularly insulin, metformin or SGLT2 inhibitors) after seeking clinical advice if you're unable to eat or drink normally
Endocrinology 148:20452055 Meinhardt U, Ebl A, Besson A, Strasburger CJ, Sraer JD, Mullis PE (2003) Regulation of growth-hormone-receptor gene expression by growth hormone and pegvisomant in human mesangial cells
261:C1130C1137
These results significantly exceed those seen with lifestyle modification alone, though they are generally less than those typically achieved with bariatric surgery
A degraded peptide doesn't just fail to produce results