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A fourth patient intentionally injected the maximum dose of 4.5 mg of dulaglutide, which was not prescribed to her, to induce ketosis

By downregulating PPAR, miR-21 in hepatocytes together with miR-34a could promote TG accumulation in the early stages of MASLD but also induce inflammation and fibrosis progression [290, 307]

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Importantly, behavioral gains were observed to regress after discontinuation of treatment, indicating that ongoing supplementation may be necessary to sustain benefits

It plays a role in the angiogenesis and vasculogenesis processes, where it regulates the expression of key molecules on the cell surface to modulate cell adhesion and motility 42