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It can be found in tea and red wine Sources Cited: Clinical, Cosmetic, and Investigational Dermatology, September 2015, pages 463-470 Journal of the America Academy of Dermatology, November 2012, pages 1,103-1,024 Skin Research and Technology, August 2008, pages 376-380 Dermatologic Surgery, July 2005, pages 814-817 Canadian Family Physician, July 2006, pages 855-856 Dermatologic Surgery, April 1999, pages 311-315

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Figure 3 shows that Ca 2+ release from the endoplasmic reticulum, which is modulated in some degree by the activity of Prx II, induces HaCaT cell apoptosis

Nature 464 , 431435 (2010)