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Anesth Analg 136(4):628635

Multi-omics studies revealed that SARS-CoV-2 infection provokes significant changes in numerous metabolites including those impacting on virus propagation (one-carbon metabolism) and GSH synthesis (amino acids glutamic acid, cysteine and glycine) that could be used as early prognosis biomarkers in COVID-19 at diagnose to predict severe COVID-19 and LONG COVID (Doan et al., 2021

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According to the FDA prescribing information, nausea occurred in 12-24% of patients, diarrhea in 11-17%, vomiting in 5-10%, and constipation in 5-7%, with rates varying by dose

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