Delaughter, M.C., Taffet, G.E., Fiorotto, M.L., Entman, M.L
Heatmap analysis of differential metabolites revealed that the hepatic metabolome profiles were substantially altered in ove-ECM1-MenSCs- and ECM1-KD-MenSCs treated mice compared with those in MenSCs treated mice (Fig
Since protein synthesis and oxygen-dependent protein folding are energy-intensive processes, and hypoxia significantly reduces the level of intracellular ATP, regulating mRNA translation is an important cellular response to hypoxia (71, 72)
TGF- induces GLS1 via the PI3K/mTORC2/PDGFR signaling pathway, promoting fibrotic target expression [100]
7 BurgD.RiepsaameJ.PontC.MulderG.van de WaterB
Additionally, the disease is characterized by brain atrophy, inflammation, oxidative damage, and disruption of the blood-brain barrier 2