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About one in three patients lost 25% or more of their starting body weight

Notably, catalases specificity for hydrogen peroxide poses constraints in conditions where other reactive oxygen species contribute to oxidative stress, necessitating strategies for more comprehensive targeting approaches [183]

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The first clinical data from a phase 2 study demonstrated that 88% of patients with a homozygous deletion or mutation in gene-associated DNA repair responded to olaparib

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