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For example, it has been found that polydatin promotes mitochondrial biogenesis and protects against mitochondrial oxidative stress via the activation of Sirtuin-1-PGC-1 pathway and Sirtuin-1-Nrf2-ARE pathway in kidney diseases (Huang et al., 2015

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Glutathione helps neutralize these reactive compounds before they cause harm

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The porcine skin was used after removing the subdermal fatty layer using a scalpel