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Activation of these receptors by GLP-1R agonists has been shown to confer protection against microvascular damage, particularly in models of diabetic retinopathy and stroke

Chronic inflammation caused by senescent T cells can compromise proteostasis and lead to mitochondrial dysfunction, contributing to immunosenescence

doi: 10.3390/nu12051275 69

doi: 10.1016/j.cotox.2017.10.003

we also determined whether the possible underlying mechanisms of its effects were associated with Nrf2-regulated anti-oxidative, mTOR-mediated anti-apoptotic, and/or autophagy systems

[DOI] [PubMed] [Google Scholar] 58.Sinha N., Dabla P.K