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However, AKERO-001 is expressed in prokaryotic cells, and our experiment suggests that eukaryotic-expressed FGF21-Fc is significantly more stable and consequently more efficacious than the prokaryotic-expressed proteins

It overstimulates NMDA receptors in the brain, leading to an influx of calcium that can literally excite brain cells to death

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Possible reasons people stop taking them include the high cost of the weekly injections and the perception that the drugs arent needed once weight goals are met, experts say

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