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The possibility that GLP-1 might hold potential for weight loss was not a new concept
doi:10.2337/diabetes.51.3.652 22
In this context, GLP-1R agonists show remarkable potential as an emerging therapeutic agent.GLP-1R agonists reduce body weight, lower blood pressure, and improve lipid levels, as well as exerting anti-inflammatory and antioxidant effects by directly acting on GLP-1R in the heart and blood vessels, thereby reducing the risk of atherosclerotic thrombotic events (Solini et al., 2023)
After calorie restriction, CTX levels continued to rise in the combination group owing to further weight loss, but these levels decreased during the final phase of the intervention from week 26 to week 52 across all four groups
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