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The other side received the same protocol but with a placebo cream

The cells were sub-cultured every 46 days using trypsin solution (0.5 w/v% trypsin5.3 mmol/L EDTA4Na solution without phenol red (10), Fujifilm Wako Pure Chemical Corporation)

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The reason we care is that citrulline is converted by the body into arginine which is one of many amino acids that the body DEFINITELY uses to make proteins

Meiselman, A three-factor approach to understanding food quality: the product, the person and the environment

Acknowledgments This work was partially supported by National Natural Science Foundation of China 81874325 (Zhiping Li), 81872915 (Ming-Wei Wang) and 82073904 (Ming-Wei Wang)