References: (1) Fourman LT, Czerwonka N, Feldpausch MN, Weiss J, et al
Dr Viral Desai highlighted that the key mechanisms include: Liver Detoxification: Glutathione conjugates with electrophilic toxins, heavy metals, and lipophilic xenobiotics in phase II biotransformation, facilitating biliary and renal excretion
GSH could also be converted to oxidized GSH (GSSG) via various glutathione peroxidases (GPX) in this process (Figure 3)
Copper homeostasis and cuproptosis represent emerging targets for therapeutic intervention in inflammatory diseases
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Antioxidant Properties Glutathione's role as an antioxidant can also play a dual role in antibiotic treatment