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Supplementary material The Supplementary Material for this article can be found online at: Abbreviations SAE, sepsis-associated encephalopathy

In contrast, the SMOTE-ENN resampling strategy significantly improved model performance, with RF, GBoost, and KNN achieving AUC over 0.995 and balanced metrics, such as recall beyond 0.98 and F1-scores exceeding 0.97, while even simpler models like LR and DT showed marked improvements in recall and F1-scores, showcasing the robustness of this technique in managing imbalanced datasets

The introduction of ethanol resulted in a substantial enhancement in solubility, ranging from 5.76 10 5 to 12.79 10 5 mole fractions

In turn, they stimulate alterations that contribute to the stromal changes and tissue biomechanical alterations (such as changes in the rigidity) in response to organ-specific needs and parenchymal requirements (33)

Associated with a lower risk of cardiovascular diseases, including stroke and heart disease