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In contrast, in models with GLS mutations, glutamate metabolism in tumor cells is restricted, which increases Gln concentration in the microenvironment and T-cell uptake and antitumor activity

Mean body weight decreased from 98.64 23.28 kg at baseline to 86.02 19.47 kg at follow-up, corresponding to a mean reduction of 12.63 24.03 kg

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thus, it is unknown how the variation in the availability of different dose strengths affected patients' ability to escalate to the 2.4 mg dosage

High unit concentration of vitamin C: Ascorbic acid - 500mg per vegetable capsule

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