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This is not a replacement for prescribed medical treatment for any other health condition

These limitations matter, and they are why the formal recommendation remains cautious

Someone who is anorexic is much more likely to have a heart attack and far more likely to have cholesterol issues because of that condition. A few other situations dont rule you out automatically, but they do call for extra caution and a real conversation: a history of gallbladder disease, diabetic retinopathy (rapid weight loss can temporarily make it worse), and any history of an eating disorder, which warrants screening before treatment starts

Moreover, GLP-1 expressed in the liver has been reported, while no other publications showed its expression in hepatocytes (44)

And while the medication has positive skin effects like improvements in patients who have inflammatory skin conditions, some outcomes leave patients wanting to make some aesthetic improvements

Skin changes occur for a number of reasons, not just medications